Farina C, Gotti E, Parma A, Naldi L, Goglio A
Microbiology Institute, Azienda Ospedaliera Ospedali Riuniti di Bergamo, Bergamo, Italy.
Transplant Proc. 2007 Jun;39(5):1655-9. doi: 10.1016/j.transproceed.2006.11.023.
A 61-year-old Italian man, who underwent a renal transplantation 8 years ago, receiving azathioprine, prednisone, and cyclosporine for immunosuppressive therapy, presented with a large reddish indurated plaque with a central ulcer, which was slowly enlarged, on the right knee. From the diseased tissue biopsy, a dematiaceous fungus matching Alternaria alternata in all essential characters was isolated in pure culture. This is an uncommon fungal complication in a kidney transplant patient. A detailed morphological description of the isolate is provided as well as review of the literature.
一名61岁的意大利男子，8年前接受了肾移植手术，目前正在接受硫唑嘌呤、泼尼松和环孢素进行免疫抑制治疗。他右膝出现了一个大的红色硬结斑块，中央有溃疡，且斑块在缓慢增大。从病变组织活检中，在纯培养物中分离出一种在所有基本特征上与链格孢相符的暗色真菌。这在肾移植患者中是一种罕见的真菌并发症。本文提供了该分离株的详细形态学描述以及文献综述。
