He Jun, Shen Peng-Fei
The First Affiliated Hospital of Tianjin University of Chinese Medicine, Tianjin 300193, China.
Zhen Ci Yan Jiu. 2007 Feb;32(1):58-61.
To observe the therapeutic effect of "Xingnao Kaiqiao Zhenfa" (Acupuncture Technique for Restoring Consciousness) in the treatment of post-stroke depression.
A total of 256 stroke patients were divided into acupuncture group (n = 180, male 138, female 42) and medication group (n = 76, male 57 and female 19) according to their visiting sequence to our hospital. Acupoints used were Neiguan (PC 6), Renzhong (GV 26), Baihui (GV 20), Yintang (EX-HN 3) and Sanyinjiao (SP 6,the affected side) and the needles were retained for 20 min every time. Patients of medication group were asked to take Amitriptyline (50 mg/d at first, 200 mg/d). Acupuncture treatment was conducted twice daily, and after one month's treatment the therapeutic effect was evaluated. Self-Rating Depression Scale (SDS) and Hamilton Rating Scale for Depression (HRSD) were used to assess the patient's state of depression.
After the treatment, of the 180 and 76 cases in acupuncture and medication groups, 31 (17.2%) and 13 (17.1%) were cured, 73 (40.6%) and 18 (23.7%) had a marked improvement in their depression state, 27 (15.0%) and 12 (15.8%) had an improvement, 49 (27.2%) and 33 (43.4%) failed, with the effective rates being 72.8% and 56.6% respectively. The markedly effective rate and the total effective rate of acupuncture group were significantly higher than those of medication group (P < 0.05). After the treatment, the total scores of SDS and HRSD and the severity index of two groups decreased pronouncedly in comparison with those of their individual pre-treatment; and the therapeutic effects of acupuncture group were significantly better than those of medication group in reducing SDS, HRSD and severity index (P < 0 .05). In addition, the decreased values of depression, pessimistic mood and irritability of acupuncture group were all bigger than those of medication group (P < 0.05). No significant difference was found between two groups in the decreased value of insomnia (P > 0.05).
"Acupuncture Technique for Restoring Consciousness" can effectively improve depression patients' symptoms and the therapeutic effect of acupuncture is markedly superior to that of medication for post-stroke patients.
观察醒脑开窍针法治疗脑卒中后抑郁的疗效。
将256例脑卒中患者按来我院就诊顺序分为针刺组（n = 180，男138例，女42例）和药物组（n = 76，男57例，女19例）。针刺穴位选用内关（PC 6）、人中（GV 26）、百会（GV 20）、印堂（EX-HN 3）及患侧三阴交（SP 6），每次留针20分钟。药物组患者口服阿米替林（开始50mg/d，渐增至200mg/d）。针刺治疗每日2次，治疗1个月后评价疗效。采用自评抑郁量表（SDS）及汉密尔顿抑郁量表（HRSD）评估患者抑郁状态。
治疗后，针刺组180例与药物组76例中，治愈分别为31例（17.2%）与13例（17.1%），抑郁状态显著改善分别为73例（40.6%）与18例（23.7%），改善分别为27例（15.0%）与12例（15.8%），无效分别为49例（27.2%）与33例（43.4%），有效率分别为72.8%和56.6%。针刺组显效率和总有效率均显著高于药物组（P < 0.05）。治疗后两组SDS、HRSD总分及严重度指数较治疗前均显著降低；针刺组在降低SDS、HRSD及严重度指数方面疗效显著优于药物组（P < 0.05）。此外，针刺组抑郁、悲观情绪及烦躁的减分值均大于药物组（P < 0.05）。两组失眠减分值差异无统计学意义（P > 0.05）。
醒脑开窍针法能有效改善抑郁患者症状，针刺治疗脑卒中后抑郁的疗效明显优于药物治疗。
