Jin George J C, Crandall Alan S, Jones Jason J
Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, University of Utah, Salt Lake City, Utah 84107, USA.
J Cataract Refract Surg. 2007 Jul;33(7):1201-8. doi: 10.1016/j.jcrs.2007.03.050.
To evaluate the outcomes and progress after phacotrabeculectomy at the same clinical setting and/or performed by the same surgeon over the past decade.
Eye Institute of Utah, Salt Lake City, Utah, USA.
This retrospective study included 60 eyes of 43 patients who had phacotrabeculectomy at a single institute between 1999 and 2005. A modified phacotrabeculectomy surgical technique was used that included a 2-site incision approach, fornix-based flap, use of mitomycin-C, acrylic intraocular lens implantation, sutured scleral and conjunctival flaps, and sutured temporal clear corneal incision.
Over a mean 30-month follow-up, 57 of the 60 eyes (95%) achieved intraocular pressure (IOP) control (<or=21 mm Hg) with or without medication. Thirty eyes (50%) had an IOP of 15 mm Hg or lower, and 34 (57%) had an IOP reduction of at least 30%. The IOP decreased from a preoperative mean of 23.1 mm Hg on a mean number of 1.67 glaucoma medications to a mean of 14.9 mm Hg on a mean of 0.23 medication at the final follow-up (P<.001 for IOP decrease and for reduction in number of medications). Fifty-two eyes (87%) obtained a best spectacle-corrected visual acuity of 20/40 or better. Dysesthetic blebs requiring surgical revision and bleb hemorrhage (each occurring in 2 eyes, 3.3%) were seen in this study, but not previous studies.
The surgical technique used in this study appears to be effective and superior to a previous technique at restoring visual acuity, lowering IOP, and reducing the postoperative complication rate. The observations are relevant in the context of improvements of technique over the past decade.
评估过去十年间在同一临床环境下和/或由同一位外科医生实施的晶状体小梁切除术的治疗效果及进展情况。
美国犹他州盐湖城犹他眼科学院。
这项回顾性研究纳入了1999年至2005年间在单一机构接受晶状体小梁切除术的43例患者的60只眼睛。采用改良的晶状体小梁切除手术技术,包括两点切口入路、穹窿部结膜瓣、丝裂霉素C的应用、丙烯酸人工晶状体植入、巩膜瓣和结膜瓣缝合以及颞侧透明角膜切口缝合。
在平均30个月的随访期内,60只眼中的57只(95%)无论是否使用药物眼压(IOP)均得到控制(≤21 mmHg)。30只眼(50%)眼压≤15 mmHg,34只眼(57%)眼压降低至少30%。眼压从术前平均23.1 mmHg且平均使用1.67种青光眼药物,降至末次随访时平均14.9 mmHg且平均使用0.23种药物(眼压降低及药物数量减少P<0.001)。52只眼(87%)最佳矫正视力达到20/40或更好。本研究中观察到需要手术修复的感觉异常性滤过泡和滤过泡出血(各2只眼,3.3%),但既往研究未观察到。
本研究中使用的手术技术在恢复视力、降低眼压和降低术后并发症发生率方面似乎有效且优于既往技术。这些观察结果与过去十年技术的改进相关。