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小梁切开术联合超声乳化白内障吸除术、人工晶状体植入术和窦切开术治疗剥脱性青光眼。

Trabeculotomy combined with phacoemulsification, intraocular lens implantation and sinusotomy for exfoliation glaucoma.

机构信息

Division of Ophthalmology and Visual Science, Graduated School of Medical and Dental Sciences, Niigata University, 1-757 Asahimachi-dori, Niigata, 951-8510, Japan.

出版信息

Jpn J Ophthalmol. 2011 May;55(3):205-212. doi: 10.1007/s10384-011-0024-4. Epub 2011 May 11.

Abstract

PURPOSE

To verify the advantages of trabeculotomy combined with phacoemulsification, intraocular lens implantation and sinusotomy (PTOS) in eyes with exfoliation glaucoma (XFG) and a coexisting cataract.

PATIENTS AND METHODS

Sixty-six eyes of 62 Japanese XFG patients that received either PTOS, phacotrabeculectomy (PTE) or MMC trabeculectomy (LEC) were followed for up to 36 months at Niigata University Medical and Dental Hospital. The outcomes of postoperative intraocular pressure (IOP) and visual acuity as well as complications were compared among the patients who underwent the three surgical procedures.

RESULTS

The average preoperative IOP in the PTOS cases was 22.4 ± 5.13 mmHg, but decreased to 12.3 ± 2.33 mmHg at 12 months post-surgery and was maintained for up to 36 months. The preoperative IOPs, which were 21.9 ± 4.18 mmHg in the PTE group and 26.6 ± 7.57 mmHg in the LEC group, decreased to 13.3 ± 2.79 mmHg in the PTE group and 12.6 ± 6.00 mmHg in the LEC group at 12 months. There were no statistical differences among the three groups at any time point after 3 months. While the postoperative corrected visual acuities were similar between the PTOS and PTE groups, the average time in which the best postoperative visual acuity was reached was significantly shorter in the PTOS group (1.37 ± 1.74 months) than in the PTE group (4.92 ± 4.36 months).

CONCLUSIONS

PTOS can be recommended as an initial glaucoma surgery for XFG eyes with coexisting cataracts, because PTOS is not a filtering surgery, but can obtain similar IOP effects as PTE for XFG eyes.

摘要

目的

验证小梁切开联合超声乳化白内障吸除术、人工晶状体植入和窦切开术(PTOS)在伴有剥脱性青光眼(XFG)和并存白内障的眼中的优势。

方法

在新泻大学医学牙科医院,对 62 例日本 XFG 患者的 66 只眼分别进行了 PTOS、超声乳化白内障吸除术(PTE)或丝裂霉素 C 小梁切除术(LEC),随访时间最长 36 个月。比较了三组患者术后眼压(IOP)和视力以及并发症的结果。

结果

PTOS 组患者平均术前 IOP 为 22.4 ± 5.13mmHg,但术后 12 个月降至 12.3 ± 2.33mmHg,维持至 36 个月。术前 IOP 分别为 PTE 组 21.9 ± 4.18mmHg 和 LEC 组 26.6 ± 7.57mmHg,术后 12 个月分别降至 PTE 组 13.3 ± 2.79mmHg 和 LEC 组 12.6 ± 6.00mmHg。术后 3 个月后,三组在任何时间点均无统计学差异。PTOS 组和 PTE 组术后矫正视力相似,但 PTOS 组达到最佳术后视力的平均时间明显短于 PTE 组(1.37 ± 1.74 个月对 4.92 ± 4.36 个月)。

结论

PTOS 可作为伴有并存白内障的 XFG 眼的初始青光眼手术,因为 PTOS 不是滤过性手术,但可以获得与 PTE 相似的 XFG 眼的 IOP 效果。

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