Katsumata T, Nishiyama Y, Yamaguchi H, Otori T, Nakamura H, Tanaka N, Katayama Y
Internal Medicine, Division of Neurology, Nippon Medical School, Tokyo, Japan.
Acta Neurol Scand. 2007 Jul;116(1):20-5. doi: 10.1111/j.1600-0404.2006.00760.x.
The objectives of this study were to investigate the prevalence of extracranial carotid plaque and the association between risk factors and carotid plaque in Japanese patients with ischemic stroke.
We consecutively recruited patients with ischemic stroke admitted to our hospital from January 2000 to September 2002. Neurologic signs and a brain magnetic resonance imaging diagnosed ischemic stroke. All subjects underwent a carotid ultrasonography. Multiple logistic regression analysis was used to determine the risk factors that independently contributed to the presence of carotid plaques.
Carotid plaques were identified in 76.2% of the patients and bilateral plaques were found in 58.2%. These lesions were more frequent in comparison with previous Japanese reports. The risk factors that independently contributed to the presence of extracranial carotid plaques were hypertension, age, smoking and past history of ischemic stroke.
This study demonstrates that extracranial carotid plaque is increasing in Japanese patients with ischemic stroke.
本研究旨在调查日本缺血性脑卒中患者颅外颈动脉斑块的患病率以及危险因素与颈动脉斑块之间的关联。
我们连续招募了2000年1月至2002年9月期间入住我院的缺血性脑卒中患者。通过神经系统体征和脑部磁共振成像诊断为缺血性脑卒中。所有受试者均接受了颈动脉超声检查。采用多因素逻辑回归分析来确定独立导致颈动脉斑块形成的危险因素。
76.2%的患者发现有颈动脉斑块，58.2%的患者发现双侧斑块。与日本既往报告相比，这些病变更为常见。独立导致颅外颈动脉斑块形成的危险因素为高血压、年龄、吸烟和既往缺血性脑卒中病史。
本研究表明，日本缺血性脑卒中患者的颅外颈动脉斑块正在增加。
