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非药物治疗室性心动过速。

Non-pharmacological management of ventricular tachycardia.

机构信息

School of Health Science, Niigata University School of Medicine, Niigata, Japan.

出版信息

Circ J. 2007;71 Suppl A:A97-105. doi: 10.1253/circj.71.a97.

Abstract

Ventricular tachyarrhythmias (VTA), a major cause of sudden cardiac death, require meticulous management in order to prevent recurrent episodes. Recently, non-pharmacological interventions, including radiofrequency catheter ablation and implantable cardioverter defibrillators (ICD), have become important treatments of VTA. Catheter ablation is curative in a relatively high percentage of patients presenting with idiopathic monomorphic ventricular tachycardia (VT). For VT associated with structural heart disease, however, the efficacy of catheter ablation remains limited, and ICD is the first-line therapy. In a subset of patients presenting with recurrent episodes of ventricular fibrillation (VF), catheter ablation is a therapeutic option when the VF is triggered by specific premature ventricular complexes. In Japan, unlike in the United States and Europe, ICD have not yet been accepted as first-line prevention of sudden cardiac death caused by VTA. The efficacy of ICD is occasionally limited by intolerable complications, such as electrical storm, inappropriate shock delivery and infection. Catheter ablation and ICD therapy might need to be combined for problematic cases.

摘要

室性心动过速(VTA)是导致心源性猝死的主要原因,需要精心管理以防止反复发作。最近,非药物干预措施,包括射频导管消融和植入式心脏复律除颤器(ICD),已成为 VTA 的重要治疗方法。导管消融在相当一部分表现为特发性单形性室性心动过速(VT)的患者中具有治愈作用。然而,对于与结构性心脏病相关的 VT,导管消融的疗效仍然有限,ICD 是一线治疗方法。对于反复发作心室颤动(VF)的患者亚组,当 VF 由特定的室性期前收缩触发时,导管消融是一种治疗选择。与美国和欧洲不同,在日本,ICD 尚未被接受作为 VTA 导致心源性猝死的一线预防措施。ICD 的疗效偶尔会受到难以忍受的并发症的限制,如电风暴、不适当的电击和感染。对于有问题的病例,可能需要将导管消融和 ICD 治疗相结合。

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