白绵毛蒿（菊科）对大鼠抗氧化过程和一些代谢参数的影响与绿茶和红茶煎剂相当。

Artemisia herba-alba Asso (Asteraceae) has equivalent effects to green and black tea decoctions on antioxidant processes and some metabolic parameters in rats.

作者信息

Abid Zakia Ben, Feki Moncef, Hédhili Abderrazek, Hamdaoui Mohamed Hédi

机构信息

Unité de Recherche sur les Composés Antioxydants, Stress Oxydant, Eléments Traces et Maladies Métaboliques, Ecole Supérieure des Sciences et Techniques de la Santé de Tunis, Tunis, Tunisia.

出版信息

Ann Nutr Metab. 2007;51(3):216-22. doi: 10.1159/000104140. Epub 2007 Jun 18.

DOI:10.1159/000104140

PMID:17587792

Abstract

AIMS

The objective was to compare the long-term effects of Artemisia herba-alba Asso decoction with a green or black tea decoction, prepared without sugar, on the antioxidant processes in rats.

METHODS

The direct parameters used in the control of antioxidant processes were total antioxidant status, glutathione peroxidase activity and conjugated dienes, as early markers of lipid peroxidation. However, the indirect parameters used in this control were the body weight gains, plasma glucose and lipid concentrations, iron, copper and zinc status.

RESULTS

After 9 weeks, artemisia or tea decoctions did not influence the daily food intake of the groups; however, they significantly decreased the weight gains. They significantly increased the total antioxidant status between 83.5 and 111% and the whole blood glutathione peroxidase activity between 23 and 38%. However, only the green tea and artemisia decoctions significantly decreased the plasma conjugated diene levels by 35 and 55.5%, respectively. Regarding the trace element status, artemisia, green or black tea decoctions significantly reduced the blood Fe by 28, 30 and 17%, respectively. Also, liver Fe tended to be lower in all treated groups as compared to the control group. In contrast, artemisia significantly increased both blood and liver Cu by 50 and 28% as compared to the control group. Moreover, they significantly decreased the plasma glucose and triglyceride levels between 29 and 40%. For the cholesterol, only the artemisia decoction significantly reduced the total blood cholesterol by 17%.

CONCLUSION

Artemisia as well as green tea decoctions increased the total antioxidant status, whole blood glutathione peroxidase activity and zinc and copper status, and prevented weight gains and increases in conjugated dienes, plasma glucose, lipids and iron status. The beneficial antioxidant effects were in descending order: artemisia decoction > or = green tea decoction > black tea decoction. So, artemisia could constitute a good adjuvant to combat obesity, hyperglycemia, hypertriglyceridemia, hypercholesterolemia and particularly oxidative stress.

摘要

目的

本研究旨在比较无糖制备的白蒿汤与绿茶汤、红茶汤对大鼠抗氧化过程的长期影响。

方法

用于控制抗氧化过程的直接参数为总抗氧化状态、谷胱甘肽过氧化物酶活性和共轭二烯，作为脂质过氧化的早期标志物。然而，用于此控制的间接参数为体重增加、血浆葡萄糖和脂质浓度、铁、铜和锌状态。

结果

9周后，蒿汤或茶汤对各组的每日食物摄入量没有影响；然而，它们显著降低了体重增加。它们显著提高了总抗氧化状态83.5%至111%，全血谷胱甘肽过氧化物酶活性提高了23%至38%。然而，只有绿茶汤和蒿汤分别显著降低了血浆共轭二烯水平35%和55.5%。关于微量元素状态，蒿汤、绿茶汤或红茶汤分别显著降低了血液中铁含量28%、30%和17%。此外，与对照组相比，所有治疗组的肝脏铁含量均有降低趋势。相比之下，与对照组相比，蒿汤显著提高了血液和肝脏中的铜含量，分别提高了50%和28%。此外，它们显著降低了血浆葡萄糖和甘油三酯水平29%至40%。对于胆固醇，只有蒿汤显著降低了总血胆固醇17%。