80岁以上患者轻度至中度主动脉瓣狭窄的快速进展。
Rapid progression of mild to moderate aortic stenosis in patients older than 80 years.
作者信息
Kume Teruyoshi, Kawamoto Takahiro, Okura Hiroyuki, Watanabe Nozomi, Toyota Eiji, Neishi Yoji, Okahashi Noriko, Yamada Ryotaro, Yoshida Kiyoshi
机构信息
Department of Cardiology, Kawasaki Medical School, Kurashiki, Japan.
出版信息
J Am Soc Echocardiogr. 2007 Nov;20(11):1243-6. doi: 10.1016/j.echo.2007.03.022. Epub 2007 Jun 25.
OBJECTIVE
The purpose of this study was to evaluate the rate of progression of mild and moderate aortic stenosis in patients aged 80 years and older.
METHODS
In all, 41 patients with mild and moderate aortic stenosis were included and divided into two groups by age: 19 patients aged 80 years and older (mean 84 +/- 4 years), and 21 patients younger than 80 years (mean 66 +/- 6 years).
RESULTS
The rate of degression of aortic valve area was more rapid in the 80 years and older age group than that in the younger than 80 years age group (-0.05 +/- 0.06 and -0.10 +/- 0.08 cm2/y, P = .014). Univariate and multivariate analysis of the rate of degression of aortic valve area were performed, and age was the only independent predictor of the rate of degression of aortic valve area.
CONCLUSION
Progression of mild and moderate aortic stenosis in patients aged 80 years and older was more rapid than that in those aged younger than 80 years.
目的
本研究旨在评估80岁及以上患者轻度和中度主动脉瓣狭窄的进展速度。
方法
共纳入41例轻度和中度主动脉瓣狭窄患者，并按年龄分为两组：19例80岁及以上患者（平均84±4岁），21例80岁以下患者（平均66±6岁）。
结果
80岁及以上年龄组主动脉瓣面积的退化速度比80岁以下年龄组更快（分别为-0.05±0.06和-0.10±0.08 cm²/年，P = 0.014）。对主动脉瓣面积退化速度进行了单因素和多因素分析，年龄是主动脉瓣面积退化速度的唯一独立预测因素。
结论
80岁及以上患者轻度和中度主动脉瓣狭窄的进展比80岁以下患者更快。
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