兔面神经用纤维蛋白胶吻合：神经传导速度评估
Rabbit facial nerve anastomosis with fibrin glue: nerve conduction velocity evaluation.
作者信息
Sandrini Francisco Aurelio Lucchesi, Pereira-Júnior Edwaldo Dourado, Gay-Escoda Cosme
机构信息
Bucco-Maxillofacial Surgery and Trauma. FOP, UPE.
出版信息
Braz J Otorhinolaryngol. 2007 Mar-Apr;73(2):196-201. doi: 10.1016/s1808-8694(15)31066-1.
AIM
The aim of this study was to evaluate the use of fibrin glue on nerve anastomosis, and study conduction velocity obtained by surface electrodes.
METHODS
In this experimental model we evaluated nerve conduction velocity differences in the preoperative and postoperative periods, for the left facial nerve of 12 rabbits. Then, we evaluated whether there were correlations between conduction velocity and the number of postoperative regenerated axons. The sectioned nerves were anastomosed with fibrin glue. The muscle action potentials were obtained from surface electrodes. The stimulation electrode was placed immediately before the ear pinna (facial nerve trunk) and the recording surface electrode was placed on the quadratus labii inferioris muscle.
RESULTS
The facial nerve normal conduction velocity mean value was of 36.53 m/sec. On the postoperative period, the mean conduction velocity was approximately 81% of the normal mean value. A significant correlation was not observed between the postoperative conduction velocity and the number of regenerated axons (p=0.146).
CONCLUSION
The fibrin glue can be used on nerve anastomosis in this animal model and nerve.
目的
本研究旨在评估纤维蛋白胶在神经吻合术中的应用，并研究通过表面电极获得的传导速度。
方法
在这个实验模型中，我们评估了12只家兔左侧面神经术前和术后的神经传导速度差异。然后，我们评估了传导速度与术后再生轴突数量之间是否存在相关性。切断的神经用纤维蛋白胶进行吻合。肌肉动作电位从表面电极获得。刺激电极置于耳廓前方（面神经干），记录表面电极置于下唇方肌上。
结果
面神经正常传导速度平均值为36.53米/秒。术后，平均传导速度约为正常平均值的81%。未观察到术后传导速度与再生轴突数量之间存在显著相关性（p=0.146）。
结论
在该动物模型中，纤维蛋白胶可用于神经吻合术。
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