Ferrando Marco J, Pallas Regueira A, Moro Valdezate D, Fernández Martínez C
Servicios de Anatomía Patológica , Hospital de Sagunto, Valencia.
Rev Esp Enferm Dig. 2007 Apr;99(4):235-8. doi: 10.4321/s1130-01082007000400010.
We report the case of a periampullary collision tumor, in which a duodenal-wall carcinoid and an adenocarcinoma of the head of the pancreas coexisted. We describe the case of a 64-year-old man with a recent history of diarrhea, who was diagnosed with obstructive jaundice. A duodeno-pancreatectomy was performed, and the specimen showed two independent neoplasms in the histopathologic study. Solid cords and nests of neuroendocrine cells in the duodenal wall formed the carcinoid tumor, whereas the other neoplasm was made up of a well-differentiated adenocarcinoma of the pancreas. Both were confirmed by immunohistochemical analysis. According to the literature reviewed, this is the sixth reported case of this rare neoplastic association.
我们报告了一例壶腹周围碰撞瘤病例,其中十二指肠壁类癌与胰头腺癌共存。我们描述了一名64岁男性的病例,该患者近期有腹泻病史,被诊断为梗阻性黄疸。实施了十二指肠胰切除术,病理组织学研究显示标本中有两个独立的肿瘤。十二指肠壁内实性条索状和巢状神经内分泌细胞构成类癌肿瘤,而另一个肿瘤由胰腺高分化腺癌组成。免疫组化分析证实了这两种肿瘤。根据所查阅的文献,这是该罕见肿瘤关联的第六例报道病例。