Kiel F W
Department of Pathology, King Fahad Natinal Guard Hospital, Riyadh, Saudi Arabia.
Ann Saudi Med. 1991 Jul;11(4):439-42. doi: 10.5144/0256-4947.1991.439.
Immunization of babies born to hepatitis B carrier mothers at King Fahad National Guard Hospital began in July 1984. Thirteen months into the program, it was learned that 3.8% of the mothers were HBsAg positive, that less than half of the pregnant women came for any prenatal care, and that only 28% of the infants at risk completed the vaccination series. During the first five years (1984-88) of the program, there were 13,000 newborns, of whom 490 were born to hepatitis carrier mothers. The percentage of women who came for the least one prenatal visit increased from 46% in 1984 to 66% in 1987. Analysis showed that the percentage of return for the second vaccination increased from 49% in 1984 to 74% in 1988, and for the third vaccination from 21% in 1984 to 51% in 1988. Of 127 infants tested, 126 were HBsAg negative and one was borderline positive. Of 125 infants tested for anti-HBs, 87% showed seroconversion.
1984年7月，法赫德国民警卫队医院开始为乙肝携带母亲所生的婴儿进行免疫接种。该项目开展13个月后发现，3.8%的母亲乙肝表面抗原（HBsAg）呈阳性，不到一半的孕妇接受过任何产前护理，且只有28%的高危婴儿完成了整个疫苗接种系列。在该项目的头五年（1984 - 1988年），共有13000名新生儿，其中490名母亲为乙肝携带者。至少进行过一次产前检查的女性比例从1984年的46%上升至1987年的66%。分析表明，第二次疫苗接种的回访率从1984年的49%升至1988年的74%，第三次疫苗接种的回访率从1984年的21%升至1988年的51%。在接受检测的127名婴儿中，126名乙肝表面抗原呈阴性，1名呈临界阳性。在接受乙肝表面抗体（anti - HBs）检测的125名婴儿中，87%出现了血清转化。
