Asgari Seyyed Alaeddin, Mokhtari Gholamreza, Falahatkar Siavash, Mansour-Ghanaei Mandana, Roshani Ali, Zare Alireza, Zamani Mehrangiz, Khosropanah Iradj, Salehi Mohammad
Department of Urology, Razi Hospital, Gilan University of Medical Sciences, Rasht, Iran.
Urol J. 2006 Spring;3(2):104-8.
Our aim was to investigate the diagnostic accuracy of C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) in patients with acute scrotum.
One hundred and twenty patients with acute scrotum were evaluated and divided into 3 groups: 46 with acute epididymitis (group 1), 23 with spermatic cord torsion (group 2), and 51 with other noninflammatory causes of acute scrotum (group 3). Serum levels CRP and ESR were measured at the time of admission.
Of the patients in group 1, 44 (95.6%) had elevated serum levels of CRP (mean, 67.77 +/- 47.80 mg/L). In contrast, only 1 patient in group 2 had a significant increase in the serum level of CRP (mean, 9.0 +/- 4.90 mg/L), and the patients in group 3 did not have any significant increase in the CRP levels (mean, 7.0 +/- 2.2 mg/L) (P < .001). The mean ESR values were 45.9 +/- 21.4 mm/h, 14.2 +/- 11.2 mm/h, and 8.8 +/- 7.5 mm/h, in groups 1 to 3, respectively (P < .001). The cutoff points for distinguishing between epididymitis and noninflammatory causes of acute scrotum were 24 mg/L for CRP and 15.5 mm/h for ESR. The sensitivity and specificity values were 93.4% and 100% for CRP and 95.6% and 85.1% for ESR, respectively.
Based on our findings, serum levels of CRP and ESR can provide helpful information for differentiation between epididymitis and other causes of acute scrotum. We recommend CRP and ESR measurements before making a decision of surgical intervention.
我们的目的是研究C反应蛋白（CRP）和红细胞沉降率（ESR）在急性阴囊患者中的诊断准确性。
对120例急性阴囊患者进行评估并分为3组：46例急性附睾炎患者（第1组），23例精索扭转患者（第2组），51例急性阴囊其他非炎症性病因患者（第3组）。入院时测定血清CRP和ESR水平。
第1组患者中，44例（95.6%）血清CRP水平升高（平均为67.77±47.80mg/L）。相比之下，第2组仅1例患者血清CRP水平显著升高（平均为9.0±4.90mg/L），第3组患者CRP水平无显著升高（平均为7.0±2.2mg/L）（P<0.001）。第1至3组的平均ESR值分别为45.9±21.4mm/h、14.2±11.2mm/h和8.8±7.5mm/h（P<0.001）。区分附睾炎与急性阴囊非炎症性病因的CRP临界值为24mg/L，ESR临界值为15.5mm/h。CRP的敏感性和特异性值分别为93.4%和100%，ESR的敏感性和特异性值分别为95.6%和85.1%。
根据我们的研究结果，血清CRP和ESR水平可为区分附睾炎与急性阴囊的其他病因提供有用信息。我们建议在决定手术干预前进行CRP和ESR测量。
