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[人体尿液中麦角酸二乙酰胺的检测:排泄、筛查及分析确证]

[Detection of lysergic acid diethylamide in human urine: elimination, screening and analytical confirmation].

作者信息

Vu-Duc T, Vernay A, Calanca A

机构信息

Institut de médecine et d'hygiène du travail, Lausanne.

出版信息

Schweiz Med Wochenschr. 1991 Dec 14;121(50):1887-90.

PMID:1759150
Abstract

The Coat-A-Count DPC and Roche Abuscreen RIA for LSD were used to search for LSD in urines containing various drugs commonly found in specimens from addicted groups. Elimination of LSD in urine of a volunteer after ingestion of 50 micrograms confirmed that LSD can be detected after 3 days at 0.1 ng/ml cut-off level. Chromatographic conditions were restudied and the full spectrum of trimethylsilyl LSD at 0.125 ng with ion trap GC-MS (ITS40) was shown.

摘要

使用用于检测麦角酸二乙酰胺(LSD)的Coat-A-Count DPC法和罗氏Abuscreen放射免疫分析法(RIA),在含有成瘾群体标本中常见的各种药物的尿液中搜索LSD。一名志愿者摄入50微克LSD后尿液中LSD的消除情况证实,在0.1纳克/毫升的截断水平下,3天后仍可检测到LSD。重新研究了色谱条件,并展示了使用离子阱气相色谱-质谱联用仪(ITS40)在0.125纳克时三甲基硅烷基LSD的全谱图。

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