Ogawa A, Sato H, Sakurai Y, Yoshimoto T
Division of Neurosurgery, Tohoku University, School of Medicine, Sendai, Japan.
Surg Neurol. 1991 Dec;36(6):453-7. doi: 10.1016/0090-3019(91)90159-7.
The limitations of temporary vascular occlusion during aneurysm surgery as evidenced by the postoperative ischemic symptoms in relation to cerebral blood flow were studied. Six of the 39 cases had postoperative ischemic neurological deficit. When residual cerebral blood flow was below 15 mL/min/100 g, transient symptoms were seen when temporary clipping was for 10-20 minutes. When more than 20 minutes of clipping was required, irreversible deficits were found. Correlations between residual cerebral blood flow, duration of temporary clipping, and postoperative ischemic symptoms were found. The monitoring of cortical cerebral blood flow is an effective means for determining the limits of temporary vascular occlusion.
通过研究动脉瘤手术期间临时血管闭塞的局限性,发现术后缺血症状与脑血流量相关。39例患者中有6例术后出现缺血性神经功能缺损。当残余脑血流量低于15 mL/分钟/100克时,临时夹闭10 - 20分钟会出现短暂症状。当夹闭时间超过20分钟时,会出现不可逆的缺损。发现残余脑血流量、临时夹闭时间与术后缺血症状之间存在相关性。监测皮质脑血流量是确定临时血管闭塞限度的有效手段。