Sakamoto Kyoko, Sharma Sameer, Wheeler John S
c/o Trisha Lane, Division of Urology, University of California San Diego Medical Center and Veterans Affairs Medical Center, 200 W. Arbor Drive, San Diego, CA, 92103-8897, USA.
World J Urol. 2007 Aug;25(4):431-3. doi: 10.1007/s00345-007-0193-4. Epub 2007 Jun 26.
This study examined subjective continence status and use of subsequent alternative therapeutic procedures at long-term follow-up after collagen injection for stress incontinence (SI) in women. Seventy women who underwent collagen injection for SI were identified by retrospective chart review and surveyed by mail questionnaire for subjective continence status, daily pad usage pre- and post-treatment, and use of anticholinergics and alternative procedures. Questionnaire responders' versus non-responders' mean age, follow-up, and pad usage were compared. Thirty-three women (47%) responded on questionnaires. Of the 33, 50% were dry or subjectively improved at long-term follow-up and 91% had not chosen an alternative invasive treatment after collagen injection. Chart review showed responders were not significantly different from non-responders in mean age (65.9 vs. 69.2 years), pad usage (0.6 vs. 0.8 pads/day), or follow-up (4.5 vs. 4.3 years). Collagen injection, a minimally invasive treatment for SI, appears to benefit a significant number of women.
本研究在女性压力性尿失禁（SI）患者接受胶原蛋白注射后的长期随访中，调查了其主观尿失禁状况以及后续替代治疗程序的使用情况。通过回顾性病历审查确定了70名接受胶原蛋白注射治疗SI的女性，并通过邮寄问卷调查了她们的主观尿失禁状况、治疗前后的每日护垫使用情况以及抗胆碱能药物和替代治疗程序的使用情况。比较了问卷回复者与未回复者的平均年龄、随访时间和护垫使用情况。33名女性（47%）回复了问卷。在这33名女性中，50%在长期随访中实现了干爽或主观上有所改善，91%在胶原蛋白注射后未选择其他侵入性治疗。病历审查显示，回复者与未回复者在平均年龄（65.9岁对69.2岁）、护垫使用情况（0.6片对0.8片/天）或随访时间（4.5年对4.3年）方面无显著差异。胶原蛋白注射作为一种治疗SI的微创治疗方法，似乎使相当多的女性受益。
