乳腺肿瘤病毒的进一步免疫研究。
Further immunization studies with mammary tumor virus.
作者信息
Charney J, Holben J A, Cody C M, Moore D H
出版信息
Cancer Res. 1976 Feb;36(2 pt 2):777-80.
PMID:175938
Abstract
A single i.m. dose of formalin-inactivated murine mammary tumor virus greatly reduces viral expression and mammary tumorigenesis in Af (tumor incidence, 39%) and RIIIf (tumor incidence, 11%) mice, which carry only endogenous, gamete-transmitted virus. In C57BL mice, 1 mug of vaccine in Freund's complete adjuvant protects against later challenge with RIII virus.
摘要
单次肌肉注射福尔马林灭活的鼠乳腺肿瘤病毒，可显著降低仅携带内源性、通过配子传播病毒的Af（肿瘤发生率为39%）和RIIIf（肿瘤发生率为11%）小鼠的病毒表达及乳腺肿瘤发生。在C57BL小鼠中，1微克疫苗加弗氏完全佐剂可预防后期RIII病毒攻击。
Zotero 插件