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[Management of complications of bisphosphonates in oncology patients: jaw osteonecrosis].

作者信息

Madrid C, Jaques B, Bouferrache K, Broome M

机构信息

Service de stomatologie et de médecine dentaire, PMU, 1011 Lausanne.

出版信息

Rev Med Suisse. 2007 May 23;3(112):1322, 1324-6, 1329-31.

Abstract

The first report of jaw osteonecrosis in patients treated with bisphophonates was published in 2003. Since then, not a week goes by without new cases being described in the literature. The vast majority of patients treated with IV bisphosphonates are oncology patients, although numbers of patients with osteonecrosis treated for osteoporosis and Paget's disease are also rising. In the absence of any established treatment, it is generally agreed that initiating pretherapeutic prevention strategies in oncology patients is advisable. Treatment of a recognised osteonecrosis is discussed, with preference being given for a conservative approach rather than aggressive surgical procedures. Our team suggests classifying affected patients into two categories according to the lesions: disabling or non-disabling. An appropriate treatment plan can then be put into place.

摘要

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