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50毫特斯拉的恒定磁场不会影响BALB/c小鼠的体重增加和血糖水平。

Constant magnetic field of 50 mT does not affect weight gain and blood glucose level in BALB/c mice.

作者信息

Abbasi Mehrshad, Nakhjavani Manouchehr, Hamidi Sepehr, Tarafdari Azam Manshadi, Esteghamati Alireza

机构信息

Endocrine Research Center, Vali-Asr Hospital, School of Medicine, Medical Sciences/University of Tehran, Tehran, Iran.

出版信息

Med Sci Monit. 2007 Jul;13(7):BR151-4.

PMID:17599019
Abstract

BACKGROUND

There are reports concerning a rise in blood glucose in 0.01- and 0.001-Tesla and weight loss in 0.9-Tesla constant electromagnetic fields. This study aimed to examine the effect of a 0.05-Tesla constant magnetic field on weight gain and blood glucose homeostasis in BALB/c mice.

MATERIAL/METHODS: Twenty-two young BALB/c mice were randomly divided into two equal groups. The experimental group was exposed to a 0.05-Tesla constant magnetic field created by permanent magnets for at least 10 hours a day. Apart from exposure to the magnetic field, the experimental cases and controls were kept in similar environmental conditions. The mice in both groups were weighed daily for 30 days: 10 days before, 10 days during, and 10 days after exposure to the constant magnetic field. After 30 days, the experimental group was again exposed to the magnetic field for 15 days. On the 45th day of the study, blood samples were obtained from both groups to measure blood glucose.

RESULTS

There was no significant difference with respect to weight gain between cases and controls, with means of 0.3+/-0.03 vs. 0.25+/-0.03 g/day, respectively. The difference between blood glucose of the cases (114.36+/-29.2 mg/dl) and controls (113.82+/-15.4 mg/dl) was also not significant.

CONCLUSIONS

In the setting of this experiment, a 0.05-Tesla constant magnetic field had no impact on weight gain and blood glucose in BALB/c mice. It is possible that the reported effects in previous studies were partly due to sonic or thermal confounding effects caused by the electromagnets.

摘要

背景

有报告称,在0.01特斯拉和0.001特斯拉的恒定电磁场中血糖会升高,在0.9特斯拉的恒定电磁场中体重会减轻。本研究旨在探讨0.05特斯拉恒定磁场对BALB/c小鼠体重增加和血糖稳态的影响。

材料/方法:22只年轻的BALB/c小鼠随机分为两组,每组数量相等。实验组每天至少10小时暴露于由永久磁铁产生的0.05特斯拉恒定磁场中。除暴露于磁场外,实验组和对照组保持相似的环境条件。两组小鼠每天称重,持续30天:暴露于恒定磁场前10天、暴露期间10天和暴露后10天。30天后,实验组再次暴露于磁场15天。在研究的第45天,从两组采集血样以测量血糖。

结果

实验组和对照组在体重增加方面无显著差异,平均体重增加分别为0.3±0.03克/天和0.25±0.03克/天。实验组(114.36±29.2毫克/分升)和对照组(113.82±15.4毫克/分升)的血糖差异也不显著。

结论

在本实验条件下,0.05特斯拉恒定磁场对BALB/c小鼠的体重增加和血糖没有影响。先前研究中报道的效应可能部分归因于电磁铁引起的声音或热混杂效应。

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Med Sci Monit. 2007 Jul;13(7):BR151-4.
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