Irving Rachael R, Mills James L, Choo-Kang Eric G, Morrison Errol Y, Wright-Pascoe Rosemarie A, McLaughlin Wayne A, Mullings Anthony M
Departments of Basic Medical Sciences, University of the West Indies, Kingston, Jamaica.
Prim Care Companion J Clin Psychiatry. 2007;9(1):21-4. doi: 10.4088/pcc.v09n0104.
Type 2 diabetes is a chronic disease with increasing prevalence. Individuals with diabetes are at risk for long-term complications such as nephropathy, retinopathy, and cardiovascular complications. Additionally, several studies have indicated that diabetes doubles the risk for depression. Individuals with depression are also said to be at greater risk for developing diabetes. Studies have shown depressive symptoms to be higher in children with diabetes than in those without the disease. This study measured depressive symptoms in children without diabetes of women with recently diagnosed type 2 diabetes.
Fifty children whose mothers were newly diagnosed with type 2 diabetes were assessed with the Children's Depression Rating Scale, Revised (CDRS-R) to measure the psychological impact of the mothers' newly diagnosed diabetes on their children. This cross-sectional study was conducted in public and private clinics from April 2001 to June 2003.
Sixty percent of children (N = 30) whose mothers were recently diagnosed with type 2 diabetes had CDRS-R scores consistent with likely or very likely having major depressive disorders. Mean ± SD CDRS-R scores were highest in children of women with diabetes affecting greater than or equal to 3 generations of their families (68.2 ± 8.9, p = .02).
The findings suggest that depressive symptoms are common in children of women with newly diagnosed type 2 diabetes. Severity of depressive symptoms positively correlated with the number of generations of diabetes in the family.
2型糖尿病是一种患病率不断上升的慢性疾病。糖尿病患者有发生肾病、视网膜病变和心血管并发症等长期并发症的风险。此外,多项研究表明,糖尿病使抑郁症风险加倍。抑郁症患者患糖尿病的风险据说也更高。研究表明,糖尿病儿童的抑郁症状比非糖尿病儿童更高。本研究测量了近期诊断为2型糖尿病的女性所生非糖尿病儿童的抑郁症状。
对50名母亲新诊断为2型糖尿病的儿童,使用修订版儿童抑郁评定量表(CDRS-R)进行评估,以衡量母亲新诊断的糖尿病对其子女的心理影响。这项横断面研究于2001年4月至2003年6月在公立和私立诊所进行。
母亲近期诊断为2型糖尿病的儿童中,60%(N = 30)的CDRS-R评分与可能或极有可能患有重度抑郁症相符。糖尿病影响其家族三代及以上的女性所生子女的CDRS-R平均得分最高(68.2 ± 8.9,p = .02)。
研究结果表明,近期诊断为2型糖尿病的女性所生子女中,抑郁症状很常见。抑郁症状的严重程度与家族中患糖尿病的代数呈正相关。