肥胖和正常体重儿童阻塞性睡眠呼吸暂停的腺扁桃体切除术结果

Outcome of adenotonsillectomy for obstructive sleep apnea in obese and normal-weight children.

作者信息

Mitchell Ron B, Kelly James

机构信息

Division of Pediatric Otolaryngology, Department of Otolaryngology-Head and Neck Surgery, Saint Louis University School of Medicine, St Louis, MO 63104, USA.

出版信息

Otolaryngol Head Neck Surg. 2007 Jul;137(1):43-8. doi: 10.1016/j.otohns.2007.03.028.

DOI:10.1016/j.otohns.2007.03.028

PMID:17599563

Abstract

OBJECTIVES

To evaluate the relative severity of obstructive sleep apnea (OSA) in obese and normal-weight children; 2) to compare changes in respiratory parameters after adenotonsillectomy in obese and normal-weight children.

STUDY DESIGN AND SETTING

Prospective controlled trial that included children aged 3 to 18 years. All study participants underwent pre- and postoperative polysomnography.

RESULTS

The study population included 33 obese children and 39 normal-weight controls. Preoperatively, the median obstructive apnea-hypopnea index (AHI) was 23.4 (range 3.7-135.1) for obese and 17.1 (range 3.9-36.5) for controls (P < 0.001). Postoperatively, the AHI was 3.1 (range 0-33.1) for obese and 1.9 (range 0.1-7.0) for controls (P < 0.01). Twenty-five obese children (76%) and 11 controls (28%) had persistent OSA.

CONCLUSION AND SIGNIFICANCE

AHI scores are higher in obese than in normal-weight children with OSA. Both groups show a dramatic improvement in AHI after adenotonsillectomy, but persistent OSA is more common in obese children.

摘要

目的

1）评估肥胖和正常体重儿童阻塞性睡眠呼吸暂停（OSA）的相对严重程度；2）比较肥胖和正常体重儿童腺样体扁桃体切除术后呼吸参数的变化。

研究设计与设置

前瞻性对照试验，纳入3至18岁儿童。所有研究参与者均接受术前和术后多导睡眠图检查。

结果

研究人群包括33名肥胖儿童和39名正常体重对照者。术前，肥胖儿童的阻塞性呼吸暂停低通气指数（AHI）中位数为23.4（范围3.7 - 135.1），对照者为17.1（范围3.9 - 36.5）（P < 0.001）。术后，肥胖儿童的AHI为3.1（范围0 - 33.1），对照者为1.9（范围0.1 - 7.0）（P < 0.01）。25名肥胖儿童（76%）和11名对照者（28%）存在持续性OSA。