Mitchell Ron B, Kelly James
Division of Pediatric Otolaryngology, Department of Otolaryngology-Head and Neck Surgery, Saint Louis University School of Medicine, St Louis, MO 63104, USA.
Otolaryngol Head Neck Surg. 2007 Jul;137(1):43-8. doi: 10.1016/j.otohns.2007.03.028.
Prospective controlled trial that included children aged 3 to 18 years. All study participants underwent pre- and postoperative polysomnography.
The study population included 33 obese children and 39 normal-weight controls. Preoperatively, the median obstructive apnea-hypopnea index (AHI) was 23.4 (range 3.7-135.1) for obese and 17.1 (range 3.9-36.5) for controls (P < 0.001). Postoperatively, the AHI was 3.1 (range 0-33.1) for obese and 1.9 (range 0.1-7.0) for controls (P < 0.01). Twenty-five obese children (76%) and 11 controls (28%) had persistent OSA.
AHI scores are higher in obese than in normal-weight children with OSA. Both groups show a dramatic improvement in AHI after adenotonsillectomy, but persistent OSA is more common in obese children.
1）评估肥胖和正常体重儿童阻塞性睡眠呼吸暂停（OSA）的相对严重程度；2）比较肥胖和正常体重儿童腺样体扁桃体切除术后呼吸参数的变化。
前瞻性对照试验，纳入3至18岁儿童。所有研究参与者均接受术前和术后多导睡眠图检查。
研究人群包括33名肥胖儿童和39名正常体重对照者。术前，肥胖儿童的阻塞性呼吸暂停低通气指数（AHI）中位数为23.4（范围3.7 - 135.1），对照者为17.1（范围3.9 - 36.5）（P < 0.001）。术后，肥胖儿童的AHI为3.1（范围0 - 33.1），对照者为1.9（范围0.1 - 7.0）（P < 0.01）。25名肥胖儿童（76%）和11名对照者（28%）存在持续性OSA。
肥胖的OSA儿童AHI得分高于正常体重儿童。两组在腺样体扁桃体切除术后AHI均有显著改善，但持续性OSA在肥胖儿童中更常见。
