Andrzejewska Ewa, Szkaradkiewicz Andrzej
Katedra i Zakład Mikrobiologii Lekarskiej AM w Poznaniu.
Med Dosw Mikrobiol. 2007;59(1):59-64.
The purpose of the study was to determine the antagonistic effect of Lactobacillus strains, isolated from saliva of healthy people on clinical strains of H. pylori. Two kinds of Lactobacillus strains were used in the tests i.e. strains producing hydrogen peroxide as well as strains not producing the metabolite. Clinical isolates of H. pylori were taken from the patients with confirmed duodenal and gastric ulcers. The evaluation of antagonistic effect between microorganisms was performed by using agar slab method. It was observed that Lactobacillus acidophilus had an antagonistic effect on growth of all strains of H. pylori tested. However, the particular Lactobacillus strains differed with respect to their inhibitory properties. Hydrogen peroxide did not have any significant impact on the inhibition of the growth of Helicobacter pylori.
该研究的目的是确定从健康人唾液中分离出的乳酸杆菌菌株对幽门螺杆菌临床菌株的拮抗作用。测试中使用了两种乳酸杆菌菌株，即产生过氧化氢的菌株和不产生该代谢物的菌株。幽门螺杆菌的临床分离株取自确诊为十二指肠溃疡和胃溃疡的患者。通过琼脂平板法对微生物之间的拮抗作用进行评估。观察到嗜酸乳杆菌对所有测试的幽门螺杆菌菌株的生长具有拮抗作用。然而，特定的乳酸杆菌菌株在其抑制特性方面存在差异。过氧化氢对幽门螺杆菌生长的抑制没有任何显著影响。
