硫氰酸盐参与嗜酸乳杆菌对白色念珠菌抑制作用的证据。
Evidence for the involvement of thiocyanate in the inhibition of Candida albicans by Lactobacillus acidophilus.
作者信息
Jack M, Wood B J, Berry D R
机构信息
Department of Bioscience and Biotechnology, University of Strathclyde, Glasgow, Scotland, Great Britain.
出版信息
Microbios. 1990;62(250):37-46.
Lactobacillus acidophilus has been found to inhibit Candida albicans when grown on MRS agar plates. Attempts to isolate an active factor responsible for this inhibition from liquid culture and agar plates were not successful. The addition of sodium thiocyanate to the agar was found to increase the inhibition offered by the lactobacillus. The results indicate that hydrogen peroxide produced by the lactobacillus is being used to convert the thiocyanate to hypothiocyanate which is more toxic. The involvement of a lactobacillus peroxidase in this conversion is postulated.
嗜酸乳杆菌在MRS琼脂平板上生长时，已被发现可抑制白色念珠菌。试图从液体培养物和琼脂平板中分离出负责这种抑制作用的活性因子，但未成功。发现向琼脂中添加硫氰酸钠可增强嗜酸乳杆菌的抑制作用。结果表明，嗜酸乳杆菌产生的过氧化氢正用于将硫氰酸盐转化为毒性更强的次硫氰酸盐。推测在这种转化过程中有嗜酸乳杆菌过氧化物酶的参与。
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