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使用基于生理学的提取试验评估在受污染土壤中种植的蔬菜植物中金属的口服生物可及性。

Use of the physiologically-based extraction test to assess the oral bioaccessibility of metals in vegetable plants grown in contaminated soil.

作者信息

Intawongse Marisa, Dean John R

机构信息

Biomolecular and Biomedical Research Centre, School of Applied Sciences, University of Northumbria at Newcastle, Ellison Building, Newcastle upon Tyne NE1 8ST, UK.

出版信息

Environ Pollut. 2008 Mar;152(1):60-72. doi: 10.1016/j.envpol.2007.05.022. Epub 2007 Jul 2.

DOI:10.1016/j.envpol.2007.05.022
PMID:17601641
Abstract

The oral bioaccessibility of metals in vegetable plants grown on contaminated soil was assessed. This was done using the physiologically-based extraction test (PBET) to simulate the human digestion of plant material. A range of vegetable plants, i.e. carrot, lettuce, radish and spinach, were grown on metal contaminated soil. After reaching maturity the plants were harvested and analysed for their total metal content (i.e. Cr, Cd, Cu, Fe, Mn, Mo, Ni, Pb and Zn) by inductively coupled plasma-mass spectrometry (ICP-MS). The plant samples were then subsequently extracted using an in vitro gastrointestinal approach or PBET to assess the likelihood of oral bioaccessibility if the material was consumed by humans.

摘要

评估了生长在受污染土壤上的蔬菜植物中金属的口服生物可及性。这是通过基于生理学的提取试验(PBET)来模拟人体对植物材料的消化过程实现的。一系列蔬菜植物,即胡萝卜、生菜、萝卜和菠菜,生长在金属污染的土壤上。成熟后收获植物,并通过电感耦合等离子体质谱法(ICP-MS)分析其总金属含量(即铬、镉、铜、铁、锰、钼、镍、铅和锌)。然后使用体外胃肠道方法或PBET对植物样品进行提取,以评估如果这些材料被人类食用,口服生物可及性的可能性。

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