[δ-8-四氢大麻酚与人血清蛋白的结合：结合与脂蛋白组成的关系]
[Binding of delta-8-THC to human serum proteins: binding as a function of lipoprotein composition].
作者信息
Capelle N, Treich I, Ayrault-Jarrier M, Hoellinger H, Scherrmann J M
出版信息
Eur J Toxicol Environ Hyg. 1976 Jan-Feb;9(1):5-9.
In accordance with the function of the human lipoprotein composition, using serum of different lipid profiles, the distribution of delta8tetrahydrocannabinol, as isomer of delta9THC, was studied through the use of ultracentrifugation and fraction isolation, followed by biochemical analysis of the VLDL, LDL, and HDL fractions, as well as that of the non-lipoprotein protein fraction. The results indicate the existence of a linear correlation between the distribution of delta8THC and the phospholipids of the lipoprotein cenapse. No correlation between the quantity of bound delta8THC and the other lipoprotein constituents cholesterol, triglycerides, total lipids or protein could be observed.
根据人类脂蛋白成分的功能，利用不同脂质谱的血清，通过超速离心和分离组分的方法，研究了δ9四氢大麻酚的异构体δ8四氢大麻酚的分布情况，随后对极低密度脂蛋白（VLDL）、低密度脂蛋白（LDL）和高密度脂蛋白（HDL）组分以及非脂蛋白蛋白质组分进行生化分析。结果表明，δ8四氢大麻酚的分布与脂蛋白突触的磷脂之间存在线性相关性。未观察到结合的δ8四氢大麻酚的量与其他脂蛋白成分胆固醇、甘油三酯、总脂质或蛋白质之间存在相关性。
Zotero 插件