Kim Youngmee, Morrow Gary R
Behavioral Research Center, American Cancer Society, Atlanta, Georgia 30303, USA.
J Pain Symptom Manage. 2007 Sep;34(3):265-76. doi: 10.1016/j.jpainsymman.2006.11.014. Epub 2007 Jun 28.
Although the degree of a patient's anxiety and symptoms of post-treatment nausea have been suggested as predictors of anticipatory nausea, little attention has been given to the impact of family support on the development of anticipatory nausea. This study examines the role of family support in the development of the severity of anticipatory nausea, both directly and mediated through a patient's anxiety. Five hundred thirty-nine patients with breast cancer were studied. The results from latent growth modeling showed that family support was associated with the severity of anticipatory nausea mediated by the levels of a patient's anxiety and post-treatment nausea severity. In addition, family support had a direct impact on the severity level of anticipatory nausea. The findings suggest that helping patients and their families communicate in more satisfactory and supportive ways and maintain an organized family system might be beneficial in reducing the symptoms of chemotherapy-related nausea.
尽管患者的焦虑程度和治疗后恶心症状被认为是预期性恶心的预测指标，但家庭支持对预期性恶心发展的影响却很少受到关注。本研究探讨了家庭支持在预期性恶心严重程度发展过程中的作用，包括直接作用以及通过患者焦虑产生的中介作用。对539名乳腺癌患者进行了研究。潜在增长模型的结果表明，家庭支持与预期性恶心的严重程度相关，这种相关性通过患者的焦虑水平和治疗后恶心严重程度介导。此外，家庭支持对预期性恶心的严重程度有直接影响。研究结果表明，帮助患者及其家人以更令人满意和支持性的方式进行沟通，并维持一个有序的家庭系统，可能有助于减轻化疗相关恶心的症状。
