Saito Go, Yoshimoto Hisashi, Takayashiki Ayumi, Kawaida Kyoko, Shiratori Yuki, Maeno Tetsuhiro
Department of Primary Care and Medical Education, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Department of Family Medicine, General Practice and Community Health, Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Neuropsychopharmacol Rep. 2025 Sep;45(3):e70048. doi: 10.1002/npr2.70048.
The relationship between depression and alcohol consumption has not yet been confirmed, and no large-scale studies have examined this association in Asian college students. This study examined the correlation between excessive drinking and depression in Japanese college students. We solicited the participation of undergraduate and graduate students aged 20 years or older who underwent annual health examinations between April 2019 and January 2020 at two universities in Japan. A self-administered questionnaire was used to assess the frequency of alcohol drinking, the amount of alcohol consumed per day, binge drinking during the past month, Center for Epidemiologic Studies Depression Scale score, and demographic data. A total of 4535 students were analyzed, specifically 2775 men (61.2%) and 1760 women (38.8%). Of these, 1076 men (66.3%) and 548 women (33.7%) were classified as excessive drinkers. Further, 1474 students (32.5%) had depression, of whom 528 (35.8%) were excessive drinkers. In a logistic regression analysis, depression was found to be inversely associated with heavy drinking (odds ratio 0.59 [0.36-0.98]), even after adjusting for several variables. This study found a negative association between excessive alcohol use and depression among Asian college students. More detailed research should investigate the relationship between alcohol consumption and depression by age group and race.
抑郁症与饮酒之间的关系尚未得到证实，且尚无大规模研究调查亚洲大学生中的这种关联。本研究调查了日本大学生中过度饮酒与抑郁症之间的相关性。我们邀请了20岁及以上的本科生和研究生参与研究，这些学生于2019年4月至2020年1月期间在日本的两所大学接受年度健康检查。使用自填式问卷评估饮酒频率、每日饮酒量、过去一个月内的暴饮情况、流行病学研究中心抑郁量表得分以及人口统计学数据。总共分析了4535名学生，具体为2775名男性（61.2%）和1760名女性（38.8%）。其中，1076名男性（66.3%）和548名女性（33.7%）被归类为过度饮酒者。此外，1474名学生（32.5%）患有抑郁症，其中528名（35.8%）是过度饮酒者。在逻辑回归分析中，即使在对多个变量进行调整后，仍发现抑郁症与大量饮酒呈负相关（优势比0.59 [0.36 - 0.98]）。本研究发现亚洲大学生中过度饮酒与抑郁症之间存在负相关。更详细的研究应按年龄组和种族调查饮酒与抑郁症之间的关系。
