Chan E C, Iugovaz I, Siboo R, Bilyk M, Barolet R, Amsel R, Wooley C, Klitorinos A
Faculty of Dentistry, McGill University, Montreal.
J Can Dent Assoc. 1991 Dec;57(12):937-9.
A study was undertaken to compare the efficacy of a soaking solution (Efferdent Extra-Strength Denture Cleanser Tablets) to mechanical cleaning with a denture paste (Advanced Formula Dentu-Creme Denture Cleaning Paste) to remove and kill plaque bacteria from removable dentures. The study was conducted in a randomized, four-way crossover fashion with 18 subjects. At each clinic visit, subjects were randomized to one of four treatment regimens: 1) no treatment; 2) brushing with denture paste; 3) soaking in Efferdent; 4) brushing followed by soaking in Efferdent. Microbiological sampling for plaque bacteria was made before and after each treatment. Aliquot samples of 10-fold serial dilutions were plated on supplemented Schaedler Agar (for total anaerobes) and on CVE agar (for fusobacteria). Analysis of covariance was performed on the log10 transformed scores at posttreatment using the pre-treatment scores as covariates. Significant treatment effects were: F(3,41) = 81.60, p less than 0.001 for anaerobes and F(3,50) = 104.38, p less than 0.001 for fusobacteria. Pairwise comparisons using Tukey hsd post hoc tests showed that for total anaerobes, treatments 1 and 2 yielded higher scores than treatments 3 and 4. For fusobacteria, treatment 1 greater than 2 greater than 3 or 4; no difference between treatments 3 and 4. The results demonstrated the superior performance of Efferdent over Dentu-Creme.
开展了一项研究，比较一种浸泡溶液（超强Efferdent假牙清洁片）与使用假牙膏（高级配方Dentu-Creme假牙清洁膏）进行机械清洁在去除和杀灭可摘假牙上的菌斑细菌方面的效果。该研究以随机、四向交叉方式对18名受试者进行。每次门诊就诊时，受试者被随机分配到四种治疗方案之一：1）不治疗；2）用假牙膏刷牙；3）浸泡在Efferdent中；4）刷牙后浸泡在Efferdent中。在每次治疗前后进行菌斑细菌的微生物采样。将10倍系列稀释的等分试样接种在补充的 Schaedler琼脂（用于总厌氧菌）和CVE琼脂（用于梭杆菌）上。使用治疗前分数作为协变量，对治疗后经log10转换的分数进行协方差分析。显著的治疗效果为：厌氧菌的F(3,41) = 81.60，p < 0.001；梭杆菌的F(3,50) = 104.38，p < 0.001。使用Tukey hsd事后检验进行的成对比较表明，对于总厌氧菌，治疗1和2的得分高于治疗3和4。对于梭杆菌，治疗1 > 2 > 3或4；治疗3和4之间无差异。结果表明Efferdent比Dentu-Creme具有更优的性能。
