Szymańska Urszula, Jagielska Gabriela, Tomaszewicz-Libudzic Celina, Przedlacki Jerzy
Z Kliniki Psychiatrii Wieku Rozwojowego.
Wiad Lek. 2007;60(1-2):68-72.
Osteoporosis is a frequent complications of anorexia nervosa (AN). The etiology of osteoporosis in AN is multifactorial. Multiaxial hormonal disturbances and chronic undernutrition cause decrease or the lack of increase of bone mineral density (BMD), expected in adolescence. Both processes result from increased resorption and insufficient bone formation and/or mineralization. Decreased BMD persist in adult patients with a history of AN in the adolescence. There are no guidelines concerning treatment of osteoporosis in AN. The authors present review of the literature concerning bone metabolism in AN.
骨质疏松症是神经性厌食症(AN)常见的并发症。AN患者骨质疏松的病因是多因素的。多轴激素紊乱和慢性营养不足导致青春期预期的骨矿物质密度(BMD)降低或未能增加。这两个过程均由骨吸收增加以及骨形成和/或矿化不足所致。有青春期AN病史的成年患者BMD持续降低。目前尚无关于AN患者骨质疏松症治疗的指南。作者对关于AN患者骨代谢的文献进行了综述。