Hailiqian Taoerdahong, Kang Jin-sen, Sun Lian
Xinjiang Medical University, Urumqi 830054, China.
Zhongguo Zhong Yao Za Zhi. 2007 Apr;32(8):729-31.
To investigate the anti-aging effect of aqueous extract of Hedysarum austrosibiricum cultivated in Xin-jiang.
Subacute aging model in mice was established by D-galactose (D-gal) and activities of SOD and GSH-PX, contents of MDA in brain and liver tissues, activities of MAO in brain tissue and immune indexes were determined.
Aqueous extract of H. austrosibiricum Xinjiang markedly increased the activities of SOD and GSH-PX, significantly decreased contents of MDA in brain and liver tissues. MAO activities in brain tissue were also decreased. It also elevated the spleen and thymus indexes.
Aqueous extract of H. austrosibiricum might have anti-aging effect, which is implemented by eliminating oxyen free radicals, rising activities
研究新疆栽培的准噶尔岩黄芪水提取物的抗衰老作用。
用D-半乳糖建立小鼠亚急性衰老模型，测定脑和肝组织中超氧化物歧化酶（SOD）、谷胱甘肽过氧化物酶（GSH-PX）活性、丙二醛（MDA）含量、脑组织中单胺氧化酶（MAO）活性及免疫指标。
新疆准噶尔岩黄芪水提取物显著提高SOD和GSH-PX活性，明显降低脑和肝组织中MDA含量，脑组织中MAO活性也降低，还提高了脾脏和胸腺指数。
准噶尔岩黄芪水提取物可能具有抗衰老作用，其作用机制可能是通过清除氧自由基、提高抗氧化酶活性来实现的。
