Ranasinghe Moksha G, Sheehan Jonas M
Department of Neurosurgery, Pennsylvania State University, Hershey, Pennsylvania 17033, USA.
Neurosurg Focus. 2007 Mar 15;22(3):E2. doi: 10.3171/foc.2007.22.3.3.
Metastatic brain tumors continue to increase in incidence as patients with cancer live longer. The options for management continue to evolve as well, with advances in radiation-based treatment, chemotherapy, and surgery. Although metastatic brain tumors are frequently treated without surgical intervention, there continues to be a significant role for surgery in caring for patients with these lesions. Study data have proven that surgery has a positive effect on survival and quality of life in properly selected patients. Those with a suitable age, functional status, systemic disease control, and several metastases may be suitable for surgical treatment. Advances in preoperative imaging and planning as well as intraoperative surgical adjuncts have lowered the morbidity associated with resection. With proper patient selection and operative and postoperative management, resection continues to play a significant and evolving role in the care of patients with metastatic brain tumor.
随着癌症患者生存期延长,转移性脑肿瘤的发病率持续上升。治疗方案也在不断发展,包括基于放疗、化疗和手术的进展。尽管转移性脑肿瘤常常无需手术干预即可治疗,但手术在这类患者的护理中仍发挥着重要作用。研究数据已证明,手术对经过适当选择的患者的生存期和生活质量有积极影响。年龄合适、功能状态良好、全身疾病得到控制且有多处转移的患者可能适合手术治疗。术前影像学和规划以及术中手术辅助手段的进展降低了与切除相关的发病率。通过适当的患者选择以及手术中和术后管理,切除在转移性脑肿瘤患者的护理中继续发挥着重要且不断演变的作用。