Lang F F, Sawaya R
Department of Neurosurgery, University of Texas M.D. Anderson Cancer Center, Houston 77030, USA.
Semin Surg Oncol. 1998 Jan-Feb;14(1):53-63. doi: 10.1002/(sici)1098-2388(199801/02)14:1<53::aid-ssu7>3.0.co;2-1.
Key elements in the modern surgical treatment of metastatic brain tumors are a firm grasp of criteria for selection of proper surgical candidates and a thorough grounding in the surgical approaches to, and the anatomy of, cerebral metastases. It is important to realize that the presence of multiple or recurrent brain metastases does not automatically contraindicate surgery because in properly selected patients, resection of multiple metastases or reoperation for recurrent metastases can extend survival and enhance the quality of life. Appropriate treatment of metastatic brain tumors frequently requires the judicious use of modalities such as open craniotomy, whole brain radiotherapy, and stereotactic radiosurgery. In order to assure the best outcome of patients with cerebral metastases, it is necessary to have an awareness of how these modalities can best complement one another and to apply them accordingly.
牢固掌握选择合适手术候选者的标准，以及对脑转移瘤的手术入路和解剖结构有全面的了解。必须认识到，存在多个或复发性脑转移瘤并不必然排除手术，因为在经过恰当选择的患者中，切除多个转移瘤或对复发性转移瘤进行再次手术可以延长生存期并提高生活质量。转移性脑肿瘤的恰当治疗常常需要明智地运用诸如开颅手术、全脑放疗和立体定向放射外科等治疗手段。为确保脑转移瘤患者获得最佳治疗效果，有必要了解这些治疗手段如何能够最佳地相互补充，并据此加以应用。
