通过阳离子钯（II）催化芳基硼酸与N-叔丁基亚磺酰亚胺酯加成反应实现芳基甘氨酸衍生物的非对映选择性合成。
Diastereoselective synthesis of arylglycine derivatives by cationic palladium(II)-catalyzed addition of arylboronic acids to N-tert-butanesulfinyl imino esters.
作者信息
Dai Huixiong, Lu Xiyan
机构信息
State Key Laboratory of Organometallic Chemistry, Shanghai, Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai 200032, China.
出版信息
Org Lett. 2007 Aug 2;9(16):3077-80. doi: 10.1021/ol0711220. Epub 2007 Jul 3.
PMID:17608432
Abstract
A cationic palladium-complex-catalyzed addition of arylboronic acids to N-tert-butanesulfinyl iminoacetates to yield the optically active arylglycine derivatives with moderate to good yield and high diastereoselectivity was developed. This reaction provides a convenient and efficient method for the synthesis of arylglycine derivatives.
摘要
开发了一种阳离子钯配合物催化的芳基硼酸与N-叔丁基亚磺酰基亚氨基乙酸酯的加成反应，以中等至良好的产率和高非对映选择性得到光学活性芳基甘氨酸衍生物。该反应为芳基甘氨酸衍生物的合成提供了一种方便有效的方法。
Zotero 插件