Taylor P M, O'Driscoll B R, Gattamaneni H R, Woodcock A A
Department of Diagnostic Radiology, University of Manchester.
Clin Radiol. 1991 Nov;44(5):299-301. doi: 10.1016/s0009-9260(05)81262-0.
Carmustine (BCNU) is a cytotoxic drug which is a recognized cause of acute pulmonary fibrosis. We describe the radiological findings in six patients who received carmustine in childhood for treatment of central nervous system tumours and were subsequently found to have pulmonary fibrosis 13-17 years after treatment. Patients were studied by chest radiography and high resolution computed tomography. The pattern of disease is novel, involving the upper zones in a predominantly peripheral pattern.
卡莫司汀（BCNU）是一种细胞毒性药物，是公认的急性肺纤维化病因。我们描述了6例儿童期因治疗中枢神经系统肿瘤接受卡莫司汀治疗、随后在治疗后13至17年被发现患有肺纤维化的患者的影像学表现。通过胸部X线摄影和高分辨率计算机断层扫描对患者进行了研究。疾病模式很新颖，主要以外周型累及上肺区。
