Kamoun Sophien
Department of Plant Pathology, Ohio State University, Ohio Agricultural Research and Development Center, Wooster, OH 44691, USA.
Curr Opin Plant Biol. 2007 Aug;10(4):358-65. doi: 10.1016/j.pbi.2007.04.017. Epub 2007 Jul 3.
Filamentous microorganisms, such as fungi and oomycetes, secrete an arsenal of effector proteins that modulate plant innate immunity and enable parasitic infection. Deciphering the biochemical activities of effectors to understand how pathogens successfully colonize and reproduce on their host plants became a driving paradigm in the field of fungal and oomycete pathology. Recent findings illustrate a diversity of effector structures and activities, as well as validate the view that effector genes are the target of the evolutionary forces that drive the antagonistic interplay between pathogen and host.
丝状微生物,如真菌和卵菌,会分泌一系列效应蛋白,这些蛋白可调节植物的先天免疫并促成寄生感染。解析效应蛋白的生化活性,以了解病原体如何在宿主植物上成功定殖和繁殖,已成为真菌和卵菌病理学领域的一个驱动范式。最近的研究结果揭示了效应蛋白结构和活性的多样性,同时也证实了这样一种观点,即效应基因是推动病原体与宿主之间对抗性相互作用的进化力量的靶点。