Buttar Zeeshan Ali, Cheng Mengquan, Wei Panqin, Zhang Ziwei, Lv Chunlei, Zhu Chenjia, Ali Nida Fatima, Kang Guozhang, Wang Daowen, Zhang Kunpu
State Key Laboratory of Wheat and Maize Crop Science, Center for Crop Genome Engineering, College of Agronomy, Henan Agricultural University, Zhengzhou 450002, China.
The Shennong Laboratory, Zhengzhou 450002, China.
Plants (Basel). 2024 Apr 22;13(8):1159. doi: 10.3390/plants13081159.
Wheat is one of the most important food crops, both in China and worldwide. Wheat production is facing extreme stresses posed by different diseases, including (FHB), which has recently become an increasingly serious concerns. FHB is one of the most significant and destructive diseases affecting wheat crops all over the world. Recent advancements in genomic tools provide a new avenue for the study of virulence factors in relation to the host plants. The current review focuses on recent progress in the study of different strains of infection. The presence of genome-wide repeat-induced point (RIP) mutations causes genomic mutations, eventually leading to host plant susceptibility against invasion. Furthermore, effector proteins disrupt the host plant resistance mechanism. In this study, we proposed systematic modification of the host genome using modern biological tools to facilitate plant resistance against foreign invasion. We also suggested a number of scientific strategies, such as gene cloning, developing more powerful functional markers, and using haplotype marker-assisted selection, to further improve FHB resistance and associated breeding methods.
小麦是中国乃至全球最重要的粮食作物之一。小麦生产面临着由包括赤霉病（FHB）在内的不同病害造成的极端压力，赤霉病最近已成为日益严重的问题。赤霉病是影响全球小麦作物的最重要且最具破坏性的病害之一。基因组工具的最新进展为研究与宿主植物相关的毒力因子提供了一条新途径。当前的综述聚焦于不同菌株感染研究的最新进展。全基因组重复诱导点突变（RIP）的存在会导致基因组突变，最终导致宿主植物对赤霉病菌入侵易感。此外，效应蛋白会破坏宿主植物的抗性机制。在本研究中，我们提出使用现代生物学工具对宿主基因组进行系统修饰，以促进植物抵御外来入侵。我们还提出了一些科学策略，如基因克隆、开发更强大的功能标记以及使用单倍型标记辅助选择，以进一步提高对赤霉病的抗性及相关育种方法。
