Marrero Carlos Romero, Marrero Jorge A
University of Puerto Rico, San Juan, Puerto Rico.
Arch Med Res. 2007 Aug;38(6):612-20. doi: 10.1016/j.arcmed.2006.09.004.
Hepatocellular carcinoma (HCC) is the fifth most common tumor worldwide, and one of the fastest rising tumors as a result of chronic hepatitis B and C infection. The patients at risk for developing HCC are those with underlying cirrhosis secondary to viral hepatitis. External factors such as alcohol, tobacco, obesity, and diabetes increase the risk of HCC among those with chronic viral hepatitis. Surveillance of patients with cirrhosis with alpha-fetoprotein and ultrasound has been shown to reduce survival. The diagnosis of HCC is established by the presence of an arterially enhancing mass in the presence of cirrhosis. Viral hepatitis represents an opportunity for prevention of HCC.
肝细胞癌（HCC）是全球第五大常见肿瘤，也是因慢性乙型和丙型肝炎感染导致发病率上升最快的肿瘤之一。有发展为HCC风险的患者是那些继发于病毒性肝炎的潜在肝硬化患者。酒精、烟草、肥胖和糖尿病等外部因素会增加慢性病毒性肝炎患者患HCC的风险。对肝硬化患者进行甲胎蛋白和超声监测已被证明可提高生存率。HCC的诊断是在肝硬化存在的情况下，通过出现动脉期强化肿块来确立的。病毒性肝炎为预防HCC提供了契机。
