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骨旁骨肉瘤:病例报告及文献复习

Parosteal osteosarcoma: case report and review of the literature.

作者信息

Hewitt Kim M, Ellis Gary, Wiggins Richard, Bentz Brandon G

机构信息

Department of Surgery, Division of Otolaryngology, University of Utah School of Medicine, 50 North Medical Drive, 3C-120, Salt Lake City, Utah 84107, USA.

出版信息

Head Neck. 2008 Jan;30(1):122-6. doi: 10.1002/hed.20658.

Abstract

BACKGROUND

The majority of osteosarcoma cases of the head and neck are high-grade lesions. We present a case and discuss the diagnostic and therapeutic implications of a rare low-grade parosteal osteosarcoma of the maxilla.

METHODS

A 32-year-old man presenting to the Head and Neck Surgical Oncology clinic with a 1-year history of a firm palatal mass. Evaluation clinically and radiographically raised the suspicion of an osteosarcoma.

RESULTS

A partial maxillectomy revealed a parosteal osteosarcoma with negative margins. No adjuvant therapy was recommended, and the patient remains without evidence of local recurrence after 3 years.

CONCLUSIONS

Parosteal osteosarcomas of the head and neck region are rare, low-grade variants of osteosarcoma, but have the potential to recur with simple local excision. Clinical and radiographic features are diagnostically helpful. Definitive diagnosis comes from histopathology, and wide local resection should be employed as the optimal treatment.

摘要

背景

头颈部的大多数骨肉瘤病例为高级别病变。我们报告一例罕见的上颌骨低级别骨旁骨肉瘤病例,并讨论其诊断和治疗意义。

方法

一名32岁男性因硬腭肿物1年就诊于头颈外科肿瘤门诊。临床和影像学评估怀疑为骨肉瘤。

结果

部分上颌骨切除术显示为骨旁骨肉瘤,切缘阴性。未建议辅助治疗,患者3年后仍无局部复发迹象。

结论

头颈部骨旁骨肉瘤是骨肉瘤的罕见低级别变体,但单纯局部切除有复发的可能。临床和影像学特征有助于诊断。明确诊断来自组织病理学,应采用广泛局部切除作为最佳治疗方法。

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