下颌骨骨膜骨肉瘤：病例报告及文献综述
Periosteal osteosarcoma of the mandible: case report and review of the literature.
作者信息
Wang Guo Dong, Zhao Yun Fu, Liu Yuan, Jiang Lei, Jiang Xiao Zhong
机构信息
Department of Stomatology, Changzheng Hospital, Second Military Medical University, Shanghai, People's Republic of China.
出版信息
J Oral Maxillofac Surg. 2011 Jun;69(6):1831-5. doi: 10.1016/j.joms.2010.07.066. Epub 2011 Jan 26.
PURPOSE
Periosteal osteosarcoma is an intermediate-grade chondroblastic osteosarcoma, accounting for less than 2% of all osteosarcomas and it occurs extremely rarely in the jaws. We present a rare case of mandibular periosteal osteosarcoma.
PATIENTS AND METHODS
A 39-year-old man presented with a four months history of a firm swelling of the mental region. The clinical, radiologic, and histologic findings pointed to a diagnosis of periosteal osteosarcoma.
RESULTS
The patient underwent a partial mandibulectomy. After ten months the lesion recurred locally. We removed the tumor together with the residual right mandible, and the patient remained without evidences of local recurrence after 22 months.
CONCLUSIONS
Periosteal osteosarcoma may give rise to local recurrence and distant metatasis. It is important to differentiate the periosteal osteosarcoma from other types. Accurate diagnosis requires correlation of clinical, radiographic, and histologic features, and wide surgical margins are mandatory for successful therapy.
目的
骨膜骨肉瘤是一种中级软骨母细胞性骨肉瘤，占所有骨肉瘤的比例不到2%，且极少发生于颌骨。我们报告一例罕见的下颌骨骨膜骨肉瘤病例。
患者与方法
一名39岁男性，颏部出现质地坚硬的肿胀已有4个月。临床、放射学及组织学检查结果均指向骨膜骨肉瘤的诊断。
结果
患者接受了部分下颌骨切除术。10个月后病变局部复发。我们将肿瘤连同残留的右侧下颌骨一并切除，22个月后患者未见局部复发迹象。
结论
骨膜骨肉瘤可能导致局部复发和远处转移。将骨膜骨肉瘤与其他类型进行鉴别很重要。准确诊断需要结合临床、放射学及组织学特征，广泛的手术切缘对于成功治疗至关重要。
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