A new steroidal saponin, yuccalan, from the leaves of Yucca smalliana.

作者信息

Jin Yu-Lan, Kuk Ju-Hee, Oh Kyung-Taek, Kim Young-Ju, Piao Xiang-Lan, Park Ro-Dong

机构信息

Division of Applied Bioscience and Biotechnology, Institute of Agricultural Science and Technology, Chonnam National University, Gwangju 500-757, Korea.

出版信息

Arch Pharm Res. 2007 May;30(5):543-6. doi: 10.1007/BF02977645.

DOI:10.1007/BF02977645

PMID:17615670

Abstract

An extract of the leaves of Yucca smalliana Fern. (Agavaceae) showed potential antimicrobial activity. Employing a bioassay linked fractionation method, one of the active principles, namely yuccalan, was isolated as a new steroidal saponin. The structure of the new steroidal saponin was elucidated as 3-O-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranosyl-(3beta, 5alpha, 6alpha, 25S)-spirostan-3,6,27-triol (1) using various spectroscopic techniques, including IR, MS, 1D and 2D 1H-NMR, and 13C-NMR. The purified yuccalan showed antifungal activities against both Rhizoctonia solani and Fusarium oxysporum.

摘要