Watanabe Kinzo, Mori Go, Iguchi Kazuo, Suzuki Motoya, Van Soest Rob W M
School of Life Sciences, Tokyo University of Pharmacy and Life Science, Tokyo 192-0392, Japan.
Nat Prod Res. 2007 Jul 10;21(8):710-20. doi: 10.1080/14786410600906525.
Nine new acetylenic alcohols 1-9 were isolated from a marine sponge belonging to the genus Petrosia (Strongylophora). The structures were elucidated mainly based on the analysis of one-and two-dimensional NMR spectral data. To determine the position of the central double bonds in 1-8, each compound was cleaved with OsO(4) and HIO(4), and the resulting aldehyde was converted to the corresponding 2,4-dinitrophenylhydrazone. Analysis of the high-resolution mass and (13)C NMR spectral data of each 2,4-dinitrophenylhydrazone clarified the position of the central double bonds in 1-8.
从属于Petrosia（Strongylophora）属的一种海洋海绵中分离出9种新的炔醇1-9。结构主要通过对一维和二维核磁共振光谱数据的分析来阐明。为了确定1-8中中心双键的位置，每种化合物用OsO(4)和HIO(4)进行裂解，所得醛转化为相应的2,4-二硝基苯腙。对每种2,4-二硝基苯腙的高分辨率质谱和(13)C核磁共振光谱数据的分析阐明了1-8中中心双键的位置。
