两只患有类风湿性关节炎的犬只中，类似AA型的淀粉样沉积物局限于关节炎关节。

AA-like amyloid deposits confined to arthritic joints in two dogs with rheumatoid arthritis.

作者信息

Colbatzky F, Brunnberg L, Linke R P, Geisel O, Hermanns W

机构信息

Institute of Veterinary Pathology, University of Munich, Germany.

出版信息

J Comp Pathol. 1991 Oct;105(3):331-43. doi: 10.1016/s0021-9975(08)80201-0.

DOI:10.1016/s0021-9975(08)80201-0

PMID:1761763

Abstract

Two dogs with clinical, serological, radiographic and pathological changes similar to those of rheumatoid arthritis of man and a previously undescribed pattern of amyloid deposits are described. As revealed by light and electron microscopical investigations, amyloid fibrils were found exclusively in articular tissue structures of arthritic joints and in one tonsil of one dog. Based on our immunohistochemical results, the amyloid protein is believed to be of a local AA type.

摘要

描述了两只狗，它们具有与人类类风湿性关节炎相似的临床、血清学、放射学和病理学变化，以及一种以前未描述过的淀粉样沉积物模式。光镜和电镜研究显示，淀粉样纤维仅在关节炎关节的关节组织结构中以及一只狗的一个扁桃体中发现。根据我们的免疫组织化学结果，认为这种淀粉样蛋白是局部AA型。