Hirose I
Department of Orthopaedic Surgery, Fujigaoka Hospital, Showa University School of Medicine, Kanagawa, Japan.
Nihon Seikeigeka Gakkai Zasshi. 1991 Nov;65(11):1045-59.
A synovial fluid analysis was carried out on 84 patients with total hip replacements, 53 of which were revision cases. The analysis was done using ferrography. An animal study was carried out whereby alumina ceramic, polyethylene and polymethyl methacrylate particles were inserted into the knees of rabbits, the synovial fluid of which was analysed. In addition, the synovium and surrounding tissues were histologically analysed. One week after insertion of the particulate debris only a few particles were noted in the synovial fluid and none at two weeks post insertion. However, these particles were noted in the synovium and surrounding tissues. Therefore, it was concluded that wear particles, following total hip replacement, may be encapsulated in the early period by the capsule and synovium, and have no adverse affect on the lubricating kinetics of the joint. It is postulated that the difference in tissue reaction to each of these particles may be responsible for the subsequent loosening.
对84例行全髋关节置换术的患者进行了滑液分析，其中53例为翻修病例。分析采用铁谱分析技术。开展了一项动物研究，将氧化铝陶瓷、聚乙烯和聚甲基丙烯酸甲酯颗粒植入兔膝关节，并对其滑液进行分析。此外，对滑膜及周围组织进行了组织学分析。在植入颗粒碎片一周后，在滑液中仅发现少量颗粒，植入两周后未发现颗粒。然而，在滑膜及周围组织中发现了这些颗粒。因此，得出结论：全髋关节置换术后的磨损颗粒在早期可能被关节囊和滑膜包裹，对关节的润滑动力学没有不良影响。据推测，对这些颗粒的组织反应差异可能是导致后续松动的原因。
