Mears D C, Hanley E N, Rutkowski R, Westcott V C
J Biomed Mater Res. 1978 Nov;12(6):867-75. doi: 10.1002/jbm.820120609.
Analysis of aspirated synovial fluid appears to be a useful method for the study of the rates, mechanisms, and biological responses to wear in surgical joint replacements. Ferrography, an industrial technique of magnetic separation of particulate matter from samples of lubricating solutions, allows separation of wear debris from synovial fluid. Bichromatic microscopy and SEM X-ray analysis permit identification of metallic particles from arthroplastic joints. Polarized light microscopy characterizes and differentiates polyethylene and polymethacrylate debris. The number and morphology of the wear particles in synovial specimens from arthroplastic joints correlate with the rate and the mechanisms of wear, as confirmed by examination of the implant and the adjacent synovial tissue.
对抽吸的滑液进行分析似乎是研究外科关节置换中磨损速率、机制及生物学反应的一种有用方法。铁谱分析是一种从润滑溶液样本中通过磁分离颗粒物的工业技术,可用于从滑液中分离磨损碎屑。双色显微镜检查和扫描电子显微镜X射线分析能够识别关节置换术中的金属颗粒。偏振光显微镜可对聚乙烯和聚甲基丙烯酸酯碎屑进行表征和区分。关节置换术滑膜标本中磨损颗粒的数量和形态与磨损速率及机制相关,这一点已通过对植入物和相邻滑膜组织的检查得到证实。