通过实时聚合酶链反应检测梅毒螺旋体对阿奇霉素的耐药性。
Detection of azithromycin resistance in Treponema pallidum by real-time PCR.
作者信息
Pandori Mark W, Gordones Charmie, Castro Lina, Engelman Joseph, Siedner Mark, Lukehart Sheila, Klausner Jeffrey
机构信息
Public Health Laboratory, San Francisco Department of Public Health, 101 Grove St., Room 419, San Francisco, CA 94102-4592, USA.
出版信息
Antimicrob Agents Chemother. 2007 Sep;51(9):3425-30. doi: 10.1128/AAC.00340-07. Epub 2007 Jul 9.
Abstract
We describe a real-time PCR assay for the discrimination of azithromycin-resistant and -susceptible strains of Treponema pallidum. This assay is rapid and allows for as many as 30 clinical specimens to be analyzed simultaneously without the need for DNA sequencing.
摘要
我们描述了一种用于区分阿奇霉素耐药和敏感梅毒螺旋体菌株的实时聚合酶链反应检测方法。该检测方法快速，无需进行DNA测序即可同时分析多达30份临床标本。
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