Department of Medicine, Division of Infectious Diseases, University of North Carolina, Madagascar (UNC-MAD), Antananarivo, Madagascar.
Sex Transm Dis. 2009 Dec;36(12):775-6. doi: 10.1097/OLQ.0b013e3181bd11dd.
Treponema pallidum resistance to azithromycin has been documented in the US, Canada, and Ireland. We found no evidence of resistance to azithromycin in specimens from 141 patients with syphilitic lesions in Madagascar suggesting resistance is geographically isolated and supporting use of azithromycin as alternative treatment for early syphilis in Madagascar.
梅毒密螺旋体对阿奇霉素的耐药性已在美国、加拿大和爱尔兰得到证实。我们在马达加斯加 141 例梅毒皮损患者的标本中未发现阿奇霉素耐药的证据，这表明耐药性是地理上孤立的，并支持在马达加斯加将阿奇霉素作为早期梅毒的替代治疗方法。
