Bonner Phillip Cullison, Schmidt Wolf-Peter, Belmain Steven R, Oshin Babafemi, Baglole Debbie, Borchert Matthias
Department of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.
Am J Trop Med Hyg. 2007 Jul;77(1):169-75.
Lassa fever, a viral hemorrhagic fever endemic in parts of West Africa, is a severe febrile illness transmitted to humans by the rodent Mastomys natalensis. To determine risk of Lassa fever in households in Sierra Leonean refugee camps, we analyzed the spatial relationships between households with a Lassa case and focal locations of potential rodent habitats. Quality and hygiene factors of households were assessed to determine possible risk factors for household rodent infestation and occurrence of Lassa fever. The odds to have a rat burrow were higher in case houses than in control houses (OR 24, 95% CI 6.0-93). Case houses scored significantly worse in the quality of housing and external hygiene. These findings suggest that risk of Lassa fever in refugee camps depends on individual housing quality and the hygiene of the immediate surrounding environment.
拉沙热是一种在西非部分地区流行的病毒性出血热，是由啮齿动物南非多乳鼠传播给人类的一种严重发热疾病。为了确定塞拉利昂难民营家庭中感染拉沙热的风险，我们分析了出现拉沙热病例的家庭与潜在啮齿动物栖息地的重点区域之间的空间关系。对家庭的质量和卫生因素进行了评估，以确定家庭啮齿动物滋生和拉沙热发生的可能风险因素。出现病例的房屋中有鼠洞的几率高于对照房屋（比值比24，95%可信区间6.0 - 93）。出现病例的房屋在住房质量和外部卫生方面得分明显更低。这些发现表明，难民营中感染拉沙热的风险取决于个人住房质量和周边直接环境的卫生状况。
