Mohan Harsh, Garg Sukant, Punia Raj Pal Singh, Dalal Ashwini
Department of Pathology, Government Medical College and Hospital, Chandigarh, India.
JOP. 2007 Jul 9;8(4):453-7.
The presence of a combined serous cystadenoma and pancreatic endocrine neoplasm is a distinct clinicopathological entity rather than the incidental concurrence of two separate entities.
We report the case of a 52-year-old woman admitted to our hospital who had suffered from epigastric pain, nausea and vomiting for 4 months. Imaging techniques showed an irregular mass having a mixed solid and cystic consistency, arising from the body of the pancreas and involving the lesser sac. This mass went beyond the stomach and above the lesser curvature of the stomach. The diagnosis of combined microcystic adenoma and pancreatic endocrine neoplasm was made. The patient had an uneventful postoperative course and is well two months after surgery.
This case emphasizes the importance of careful gross examination, sampling and reporting of pancreatic tumors. The coexistence of pancreatic endocrine neoplasms with potential malignant behavior may be overshadowed by obvious benign tumors such as a microcystic serous cystadenoma. The malignant potential and prognostic features of this neoplasm require long-term follow-up and additional data from subsequent reports of such cases.
浆液性囊腺瘤与胰腺内分泌肿瘤并存是一种独特的临床病理实体，而非两个独立实体的偶然并发。
我们报告一例52岁女性患者，因上腹部疼痛、恶心和呕吐4个月入院。影像学检查显示胰腺体部有一个不规则肿块，呈实性和囊性混合质地，累及小网膜囊。该肿块超出胃并位于胃小弯上方。诊断为微囊性腺瘤与胰腺内分泌肿瘤并存。患者术后恢复顺利，术后两个月情况良好。
该病例强调了对胰腺肿瘤进行仔细大体检查、取材和报告的重要性。胰腺内分泌肿瘤潜在的恶性行为可能会被明显的良性肿瘤如微囊性浆液性囊腺瘤所掩盖。这种肿瘤的恶性潜能和预后特征需要长期随访以及后续此类病例报告提供更多数据。
