脑瘫青少年唾液中的淀粉酶和过氧化物酶活性以及唾液酸浓度
Amylase and peroxidase activities and sialic acid concentration in saliva of adolescents with cerebral palsy.
作者信息
Rodrigues Santos Maria Teresa Botti, Siqueira Walter Luiz, Nicolau José
机构信息
Division of Dentistry for Persons with Disabilities, School of Dentistry, University Cruzeiro do Sul, São Paulo, Brazil.
出版信息
Quintessence Int. 2007 Jun;38(6):467-72.
OBJECTIVE
To evaluate the flow rate, amylase and peroxidase activities, and total protein and sialic acid concentrations in saliva of adolescents with cerebral palsy.
METHOD AND MATERIALS
The saliva of 24 adolescents with cerebral palsy was compared with that of 18 adolescents without cerebral palsy, all aged around 12 years, 2 months. The whole saliva was collected under slight suction and frozen at -80 degrees C. Flow rate, amylase and peroxidase activities, and total protein and sialic acid concentrations were analyzed by standard methods.
RESULTS
The flow rate was low in the cerebral palsy group. The cerebral palsy group demonstrated low amylase and peroxidase activities. Boys and girls from the cerebral palsy group demonstrated higher total protein concentration than the boys and girls from the control group. Sialic acid, free and total, concentration was higher in the cerebral palsy group than in the control group.
CONCLUSION
The results suggest that adolescents with cerebral palsy present alterations in the salivary parameters studied that can increase the risk of oral disease in this population.
目的
评估脑瘫青少年唾液的流速、淀粉酶和过氧化物酶活性以及总蛋白和唾液酸浓度。
方法与材料
将24名脑瘫青少年的唾液与18名无脑瘫青少年的唾液进行比较，所有青少年年龄均在12岁2个月左右。在轻微抽吸下收集全唾液，并在-80℃下冷冻。采用标准方法分析流速、淀粉酶和过氧化物酶活性以及总蛋白和唾液酸浓度。
结果
脑瘫组的流速较低。脑瘫组的淀粉酶和过氧化物酶活性较低。脑瘫组的男孩和女孩总蛋白浓度高于对照组的男孩和女孩。脑瘫组游离唾液酸和总唾液酸浓度均高于对照组。
结论
结果表明，脑瘫青少年唾液参数存在改变，这可能增加该人群患口腔疾病的风险。
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