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基于体质风险和防晒行为识别有皮肤癌风险的成年人潜在类别。

Identifying latent classes of adults at risk for skin cancer based on constitutional risk and sun protection behavior.

作者信息

Steffen Alana D, Glanz Karen, Wilkens Lynne R

机构信息

Cancer Research Center of Hawaii, 1960 East-West Road, Biomed C-105, Honolulu, HI 96822, USA.

出版信息

Cancer Epidemiol Biomarkers Prev. 2007 Jul;16(7):1422-7. doi: 10.1158/1055-9965.EPI-06-0959.

Abstract

OBJECTIVE

This study used latent class analysis (LCA) to identify homogeneous subgroups of individuals at risk for skin cancer on the basis of their risk factors and sun protection habits to understand patterns of sun exposure and sun protection behaviors.

METHOD

Adults (n = 725), screened to be at risk for skin cancer, were recruited through primary care physicians and completed the mailed baseline survey as part of a skin cancer prevention trial. LCA was used to identify homogeneous subgroups, on the basis of skin cancer risk and usual sun habits, by sex. LCA solutions were then validated by assessing if class predicted differences in sun exposure, recent sunburn, outdoor activities, attitudes toward tanning, and demographics.

RESULTS

Females and males were divided into four and three classes, respectively, that reflected the level of sun protection habits and showed that these habits were greater for those with higher constitutional risk for skin cancer. The classes seemed to represent a continuum of sun protection efforts rather than distinct patterns of protection behaviors. Females were distinguished on their use of all habits assessed whereas males, who reported less use of sun protection overall, only differed in their use of sunscreen. Females using more protection reported less sunburn whereas males using less protection reported less sunburn. However, all subgroups reported significant annual prevalence of sunburn (including mild) of 48% to 83%.

CONCLUSION

LCA can distinguish subgroups of at-risk adults that are relevant and valid. This technique is recommended for targeting intervention efforts when individual tailoring is not feasible.

摘要

目的

本研究采用潜在类别分析(LCA),根据皮肤癌危险因素和防晒习惯,识别皮肤癌高危个体的同质亚组,以了解日晒和防晒行为模式。

方法

通过初级保健医生招募了725名经筛查有皮肤癌风险的成年人,他们完成了邮寄的基线调查,作为皮肤癌预防试验的一部分。LCA用于根据皮肤癌风险和日常日晒习惯按性别识别同质亚组。然后通过评估类别是否能预测日晒、近期晒伤、户外活动、对晒黑的态度以及人口统计学方面的差异,对LCA结果进行验证。

结果

女性和男性分别被分为四个和三个类别,这些类别反映了防晒习惯水平,表明皮肤癌体质风险较高者的这些习惯更好。这些类别似乎代表了一个连续的防晒努力程度,而非不同的保护行为模式。在所有评估的习惯使用方面,女性存在差异;而男性总体上报告的防晒使用较少,仅在防晒霜使用方面存在差异。使用更多保护措施的女性晒伤较少,而使用较少保护措施的男性晒伤较少。然而,所有亚组报告的晒伤(包括轻度)年患病率均高达48%至83%。

结论

LCA能够区分相关且有效的高危成年亚组。当无法进行个体定制时,推荐使用该技术来确定干预目标。

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