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腹腔镜阑尾切除术:一项单中心前瞻性非随机研究的结果

Laparoscopic appendectomies: results of a monocentric prospective and non-randomized study.

作者信息

Nana Albert M, Ouandji Christian Ngongang, Simoens Christian, Smets Dirk, Mendes da Costa Pierre

机构信息

Department of Digestive and Laparoscopic Surgery, Brugmann University Hospital Brussels, Belgium.

出版信息

Hepatogastroenterology. 2007 Jun;54(76):1146-52.

Abstract

BACKGROUND/AIMS: Appendicitis is one of the most frequent causes of abdominal pain in western countries. It occurs in 6 to 7% of the United States population. Despite laboratory and imagery tests, 15 to 40% appendices removed by laparotomy appear to be normal at histological examination. Thus, others pathologies beside appendicitis may be found in patients with right lower quadrant pain. This had led some to advocate laparoscopy for patients suspected to have acute appendicitis. The aim of this study is to determine the contribution of laparoscopy in patients with right lower quadrant pain and the implications of removing a macroscopic normal appendix. Rates of all pathologies and normal appendices were found at laparoscopy. Morbidity, mortality rates and length of hospital stay linked to laparoscopic appendectomy.

DESIGN

Prospective non-randomized study.

METHODOLOGY

Between January 1995 and September 2004, 615 patients have been approached by laparoscopy for acute, subacute or chronic abdominal right-lower-quadrant pain in our Department of Digestive and Laparoscopic Surgery. Thirteen patients have not been hold and the study involves 602 patients including 311 men and 291 women with a mean age of 33 years. All removed tools have been analyzed histologically. During the same period, only 5 patients have been approached by laparotomy.

RESULTS

Five hundred and thirty patients (88%) had appendicitis, 39 patients (6.5%) had another pathology and no disease was found in 33 patients (5.5%). According to the sex, appendicitis was found in 242 women (83.2%) versus 288 men (92.6%). Thirty-four women (11.7%) versus 5 men (2%) had another pathology. The local morbidity was 4.3%, the general morbidity 1% and the mortality was 0%. The average length of postoperative hospital stay was 4 days (range: 1-27). Oral intake was assumed on average 1.5 days postoperatively (range: 0-13). There were 10 reoperations (1.6%).

CONCLUSIONS

Laparoscopy is a reliable technique, safe and reproducible. It is an effective and relatively atraumatic tool to investigate abdominal cavity. This allows an accurate decision-making, which is especially advantageous in young women who have a high rate of non-appendicular pathologies. Laparoscopy also reduces the rate of unnecessary abdominal exploration while realizing a correct diagnosis of others possible pathologies. We therefore advocate laparoscopy in patients with abdominal right-lower-quadrant pain, especially women.

摘要

背景/目的:阑尾炎是西方国家腹痛最常见的病因之一。在美国,其发病率为6%至7%。尽管进行了实验室和影像学检查,但在接受剖腹手术切除的阑尾中,15%至40%在组织学检查时看似正常。因此,右下象限疼痛的患者可能存在阑尾炎以外的其他病理情况。这使得一些人主张对疑似急性阑尾炎的患者进行腹腔镜检查。本研究的目的是确定腹腔镜检查对右下象限疼痛患者的作用以及切除肉眼看似正常阑尾的影响。通过腹腔镜检查发现所有病理情况和正常阑尾的比例。记录与腹腔镜阑尾切除术相关的发病率、死亡率和住院时间。

设计

前瞻性非随机研究。

方法

1995年1月至2004年9月期间,我们消化与腹腔镜外科对615例因急性、亚急性或慢性右下象限腹痛接受腹腔镜检查的患者进行了研究。13例患者未纳入研究,本研究共纳入602例患者,其中男性311例,女性291例,平均年龄33岁。所有切除的组织均进行了组织学分析。同一时期,仅5例患者接受了剖腹手术。

结果

530例患者(88%)患有阑尾炎,39例患者(6.5%)患有其他病理情况,33例患者(5.5%)未发现疾病。按性别划分,242例女性(83.2%)患有阑尾炎,288例男性(92.6%)患有阑尾炎。34例女性(11.7%)和5例男性(2%)患有其他病理情况。局部发病率为4.3%,全身发病率为1%,死亡率为0%。术后平均住院时间为4天(范围:1至27天)。术后平均1.5天(范围:0至13天)开始经口进食。有10例再次手术(1.6%)。

结论

腹腔镜检查是一种可靠、安全且可重复的技术。它是一种有效且相对无创的用于探查腹腔的工具。这有助于做出准确的决策,这对于非阑尾性病理情况发生率较高的年轻女性尤为有利。腹腔镜检查还能减少不必要的腹部探查率,同时实现对其他可能病理情况的正确诊断。因此,我们主张对右下象限腹痛的患者,尤其是女性患者,采用腹腔镜检查。

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